7 位指定作者本週 PubMed 新發表——Stephen W. Smith / Pendell Meyers / Ken Grauer / Jesse McLaren / Emre Aslanger / Willy Frick / Sam Ghali。
STEMI criteria demonstrated lower sensitivity for OMI as compared to the AI algorithm (47.1% vs 94.1%, p = 0.005), and a non-significantly lower specificity (66.1% vs 73.2%, p = 0.090). The AI algorithm also demonstrated higher positive and negative likelihood ratios for OMI identification (3.51 and 0.08, respectively) than STEMI criteria (1.39 and 0.80, respectively).
BACKGROUND: Delphinium denudatum (jadwār) is a traditional South Asian herbal root containing aconitine-like alkaloids that cause sodium channel-mediated cardiotoxicity. Human toxicity data remain limited, particularly from resource-limited settings. CASE SUMMARY: A man in his late 20s presented 6 hours after accidental ingestion of Ddenudatum root with palpitations and autonomic symptoms.
RESULTS: The study included 2,523 patients, 68.3% male, with a median age of 63 years. Among AMI with culprit patients, the model correctly identified 93.8% as OMI(+). The model correctly identified 79.7% of no-AMI patients as OMI(-). The AUCROC was 0.952 (95% CI: 0.924-0.966).